91短视频 launches BaseMap ABE to enable genome-wide off-target characterization in base editing therapeutic developments 

  • Extension of the INDUCE-seq platform to support adenine base editing (ABE) workflows 

  • Researchers invited to gain early access to platform and support ongoing product development

Cambridge, UK, 10 August 2026 - 91短视频, a biotechnology company enabling gene editing teams to accelerate development of safer, more effective genetic medicines, today announced the launch of BaseMap鈩 ABE. Built on the 91短视频's INDUCE-seq庐 technology, BaseMap ABE extends the platform's capabilities to support adenine base editing (ABE) applications.  

Base editing is rapidly gaining momentum as a powerful therapeutic tool that enables precise single-base genomic changes. However, as therapeutic programs increasingly adopt ABE, researchers require reproducible and standardized methods to comprehensively characterize unintended off-target editing events.

Unlike prediction-based approaches, BaseMap ABE generates genome-wide data directly from biologically relevant cells, providing researchers with clear understanding of editor specificity under physiologically relevant conditions.

The platform enables rapid, unbiased identification of off-target events, while generating standardized and robust data to support guide optimization, editor selection and preclinical decision making.

BaseMap ABE represents the first phase of 91短视频鈥 expansion into base editing applications, building on its established INDUCE-seq technology. Through the Early Access Program, the 91短视频 will collaborate closely with researchers developing genome editing therapies, providing first-hand experience for early adopters and generating feedback to inform future product development.

Terry Pizzie, CEO, 91短视频, said:As gene editing technologies evolve, researchers need to wholly understand where and how frequently off-target editing occurs. By extending our product portfolio to support ABE, Broken String is enabling scientists to characterize editing outcomes for one of the most promising next-generation editing modalities. We are excited to get this solution into the hands of early-adopters 鈥 working closely with them to shape the future of our product and support the development of safe and effective base editing therapeutics.鈥  

For more information please visit: www.brokenstringbio.com/basemap-abe

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